Stuart is Professor of Clinical & Molecular Cardiology at Imperial College London and group head within the Cardiovascular Genetics & Genomics Unit. He is also Director of the Cardiovascular & Metabolic Disorders Programme at Duke-NUS Medical School, Singapore, and Director of the National Heart Research Institute of Singapore.
James is a Reader in Genomic Medicine at Imperial College, and a group head within the Cardiovascular Genetics & Genomics Unit. He practices clinically as a Consultant Cardiologist at Royal Brompton & Harefield Hospitals, and is cardiac lead for the West London Genome Medicine Centre.
Paul Barton is Honorary Senior Research Fellow at the National Heart and Lung Institute and Research Manager for the Cardiovascular Genetics and Genomics Group. He has particular interests in the genetics of Inherited Cardiac Conditions, gene-environment interactions and enhancing international collaboration, currently through research partners based in Florence, Madrid and the Aswan Heart Centre in Egypt.
Mona is pursuing a PhD in Clinical Research Medicine in collaboration between Imperial College London and Aswan Heart Centre. She is interested in defining the genetic architecture of cardiomyopathies in the Egyptian population.
Rachel is a molecular biologist with an interest in the genetics of inherited cardiac conditions. She oversees the wet-lab based projects in the Cardiovascular Genetics and Genomics Group at the Royal Brompton.
Ben is an NIHR Post-doctoral Academic Clinical Fellow and Specialist Registrar training in cardiology. He is currently investigating genetic influences on arrhythmias in dilated cardiomyopathy.
Leanne Felkin is a postdoctoral scientist interested in the early features of cardiomyopathies which develop before the more characteristic features of the disease. She is particularly interested in the factors released by the heart muscle into the circulation which could be used as biomarkers to personalise medicine allowing early disease detection, support risk stratification and monitor disease progression. Leanne’s current focus is to develop new, highly sensitive immunoassays for the detection of novel biomarkers released by cardiac fibroblasts in the initial stages of the fibrotic response.
Dr Katie Francis is a Cardiology SpR currently working on a PhD on the genetics of the aorta and aortic disease. She is working on a genome-wide association study of aortic traits, looking for new pathways which might be involved in cardiovascular risk or aortic disease. She has worked with the ClinGen aortopathy team, an international consortium aiming to curate published data on gene-disease relationships for inherited thoracic aortic conditions.
Dr Amrit Lota is a cardiology specialty registrar currently working on a PhD on advanced imaging and genomics in acute inflammatory cardiomyopathy. He was awarded a BHF clinical research training fellowship in 2016. His research includes multi-centre prospective recruitment of patients with acute myocarditis to investigate predictors of adverse risk and remodelling using cardiovascular magnetic resonance, as well as underlying genetic susceptibility through next generation sequencing and genome-wide association studies.
Nick is a PhD student working on bioinformatic methods for identifying novel-missense variants that are likely pathogenic by using information from paralogous genes. Additionally, he is also looking into specific variants associated with Hypertrophic cardiomyopathies (HCM) and is evaluating variant interpretation techniques for these variants using patient outcome data.
Anne Marie Moody
Anne is using genome engineering to model cardiomyopathies in stem-cell derived cardiomyocytes.
Francesco is a post-doctoral bioinformatician based in Florence, working with both the University of Florence and the group at Imperial, where he obtained his PhD. His current research is mainly focused on dissecting the genetic architecture of cardiomyopathies and on variant interpretation
Nick is a Clinical PhD Fellow, working in the molecular biology laboratory at the Hammersmith Campus. He is interested in heart failure and arrhythmia, and is investigating the role of novel biomolecules in myocardial fibrosis.
Angharad is a Clinical Geneticist with a subspecialist interest in cardiac conditions; and a postdoctoral research fellow in the Cardiovascular Genetics and Genomics Group. She is interested in the diagnosis of complex cases, delineating and understanding the variability in clinical expression of recognised syndromes (expanding the phenotype) and identifying new syndromes and diagnoses to inform both clinical practice and research.
Pantazis Theotokis is a research assistant in bioinformatics interested in developing and implementing new pipelines for the analysis of NGS data in cardiomyopathies. He is currently working on ways to improve integration and harmonisation of genetic variants from various cohorts.
Konstantinos is a NHLI post-doctoral associate, working in the molecular biology laboratory at the Hammersmith Campus. He is interested in cardiac fibrosis and is investigating the role of IL-11 in fibrosis using a variety of models.
Nicky is an Imperial College Research Fellow using bioinformatics and large sequencing datasets to investigate the contribution of rare non-coding variants to disease. Nicky is also interested in developing methods and tools that improve consistency and reproducibility in clinical variant interpretation.
Xiao is a postdoctoral bioinformatician, interested in using NGS technologies to understand genetic cause of cardiovascular disorders. Current projects involve discovery of monogenic and polygenic disease causing variants from family and case-control association studies.
Xiaolei is a research assistant interested in the statistical learning methods to facilitate variant interpretation in cardiovascular disease. She is now working on new statistical models to predict variant’s pathogenicity.